Pathogenesis of Obstructive Sleep Apnea in Obesity

摘要: Obstructive sleep apnea is a sleep-related breathing disorder characterized by repetitive upper airway obstruction and associated with significant morbidity mortality. Obesity one of the primary modifiable risk factors for management patients as there positive association between increasing obesity prevalence prevalence. Several mechanisms link pathogenesis, including potential increase in additional mechanical load on lower respiratory systems from regional adiposity, possible effects obesity-related inflammation neuromuscular neuroventilatory function airway, or combination these effects. By examining relationship obstructive well which may contribute to development its related comorbidities, we can evaluate effect weight reduction apnea.