Cytotoxicity of orthodontic materials assessed by survival tests in Saccharomyces cerevisiae.
作者： Karen M Limberger , Graziela H Westphalen , Luciane M Menezes , Renata Medina-Silva , None
DOI: 10.1016/J.DENTAL.2011.01.001
关键词:
摘要: The aim of this study was to assess the cytotoxicity orthodontic materials (brackets, wires, resin, elastomers and silver solder) using Saccharomyces cerevisiae as a model organism. induction assessed by two different tests wild-type S. strain FF18733: (1) direct exposure in YPD broth, (2) artificial commercial saliva pre-treated with materials. Only solder tested mutant strains investigate origin observed cytotoxicity. Colony forming units per mL counts were carried out all experiments compared controls detect significant survival differences. results showed that only induced cytotoxicity, which might have occurred via oxidative stress, although mechanism is not completely understood. Moreover, proved be reliable useful microorganism for evaluating clinical
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