TNF-induced activation of pulmonary microvessel endothelial cells : a role for GSK3β

作者: Arnold Johnson

DOI: 10.1152/AJPLUNG.90566.2008

关键词:

摘要: The hypothesis tested was PKCα mediates the phosphorylation of glycogen synthetase kinase 3β (GSK3β) and that GSK3β inhibition modulates response to tumor necrosis factor-α (TNF) in rat pul...

参考文章(33)
V Stambolic, J R Woodgett, Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochemical Journal. ,vol. 303, pp. 701- 704 ,(1994) , 10.1042/BJ3030701
H Grasberger, P Jung, J Vlotides, O E Janssen, R Landgraf, S Hofmann, M Bidlingmaier, The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression. European Journal of Medical Research. ,vol. 7, pp. 171- 176 ,(2002)
Ratan V. Bhat, Samantha L. Budd Haeberlein, Jesús Avila, Glycogen synthase kinase 3: a drug target for CNS therapies Journal of Neurochemistry. ,vol. 89, pp. 1313- 1317 ,(2004) , 10.1111/J.1471-4159.2004.02422.X
Dexing Fang, David Hawke, Yanhua Zheng, Yan Xia, Jill Meisenhelder, Heinz Nika, Gordon B. Mills, Ryuji Kobayashi, Tony Hunter, Zhimin Lu, Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity * Journal of Biological Chemistry. ,vol. 282, pp. 11221- 11229 ,(2007) , 10.1074/JBC.M611871200
Judit E Pongracz, Robert A Stockley, Wnt signalling in lung development and diseases Respiratory Research. ,vol. 7, pp. 15- 15 ,(2006) , 10.1186/1465-9921-7-15
Laura Dugo, Maha Abdelrahman, Oliver Murch, Emanuela Mazzon, Salvatore Cuzzocrea, Christoph Thiemermann, Glycogen synthase kinase-3β inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation Shock. ,vol. 25, pp. 485- 491 ,(2006) , 10.1097/01.SHK.0000209545.29671.31
K. A. Qatsha, C. Rudolph, D. Marme, C. Schachtele, W. S. May, Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 4674- 4678 ,(1993) , 10.1073/PNAS.90.10.4674
Masato Eto, Alexei Kouroedov, Francesco Cosentino, Thomas F. Lüscher, Glycogen Synthase Kinase-3 Mediates Endothelial Cell Activation by Tumor Necrosis Factor-α Circulation. ,vol. 112, pp. 1316- 1322 ,(2005) , 10.1161/CIRCULATIONAHA.105.564112
Rui-Hong Chen, W. Vivianne Ding, Frank McCormick, Wnt Signaling to β-Catenin Involves Two Interactive Components: GLYCOGEN SYNTHASE KINASE-3β INHIBITION AND ACTIVATION OF PROTEIN KINASE C Journal of Biological Chemistry. ,vol. 275, pp. 17894- 17899 ,(2000) , 10.1074/JBC.M905336199
Thilo Hagen, Elena Di Daniel, Ainsley A. Culbert, Alastair D. Reith, Expression and Characterization of GSK-3 Mutants and Their Effect on β-Catenin Phosphorylation in Intact Cells Journal of Biological Chemistry. ,vol. 277, pp. 23330- 23335 ,(2002) , 10.1074/JBC.M201364200