Neurologic Complications of Infective Endocarditis

作者: Allan R. Tunkel , Donald Kaye

DOI: 10.1016/S0733-8619(18)30161-0

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摘要: The average overall incidence of neurologic complications in patients with infective endocarditis is 30%, the vast majority these left-sided valvular disease. central nervous system manifestations, particularly embolic events, tends to be higher cases caused by more virulent organisms, such as S. aureus and Enterobacteriaceae. clinical presentation dependent on area involved. CT MRI scanning are useful radiologic imaging techniques for diagnosis endocarditis; cerebral angiography should used suspected intracranial mycotic aneurysm. cornerstone management appropriate antimicrobial therapy. Neurosurgical intervention may required certain aneurysms that do not disappear after therapy or enlarge bleed. Anticoagulants continued prosthetic valve who have evidence hemorrhage. avoided (unless thromboembolic events from a site other than vegetation) native owing risk hemorrhagic complications. Case fatality rates tend endocarditis. Earlier diagnostic therapeutic interventions will, it hoped, improve outcome this disorder.

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