Role of the thermic effect of food in malnutrition of patients with chronic obstructive pulmonary disease.

摘要: Malnutrition in patients with chronic obstructive pulmonary disease (COPD) is classically ascribed to an increased resting energy expenditure (REE) secondary high cost of breathing. However, malnutrition correlates only weakly the severity respiratory dysfunction, which suggests other mechanisms. The aim present study was determine possible role diet-induced thermogenesis (DIT). Therefore, we evaluated relationship between DIT and nutritional status, particular fat-free mass (FFM) estimated by bioelectrical impedance analysis 26 stable COPD (mean FEV1 +/- SEM = 36.5 3.8% predicted). Ten were undernourished (weight < 90% ideal body weight [IBW] and/or FFM 69% IBW), 16 normally nourished. Diet-induced determined comparing postprandial REE, latter being measured after overnight fast former over 4 h a mixed test meal 0.4 times REE load. No statistical differe...