Health Effects Associated with Inhalation of Airborne Arsenic Arising from Mining Operations

作者: Rachael Martin , Kim Dowling , Dora Pearce , James Sillitoe , Singarayer Florentine

DOI: 10.3390/GEOSCIENCES4030128

关键词:

摘要: Arsenic in dust and aerosol generated by mining, mineral processing metallurgical extraction industries, is a serious threat to human populations throughout the world. Major sources of contamination include smelting operations, coal combustion, hard rock as well their associated waste products, including fly ash, mine wastes tailings. The number uncontained arsenic-rich sites world growing concern, people at risk exposure. Inhalation exposures arsenic-bearing dusts aerosol, both occupational environmental settings, have been definitively linked increased systemic uptake, carcinogenic non-carcinogenic health outcomes. It therefore becoming increasingly important identify sensitive sub-populations exposure, better understand modes action for pulmonary arsenic toxicity carcinogenesis. In this paper we explore contribution smelting, mining products atmospheric arsenic. We also report on current understanding effects inhaled arsenic, citing results from various toxicological, biomedical epidemiological studies. This review particularly aimed

参考文章(222)
H.Vasken Aposhian, Baoshan Zheng, Mary M. Aposhian, X.Chris Le, Mariano E. Cebrian, William Cullen, Robert A. Zakharyan, Mingsheng Ma, Richard C. Dart, Zhai Cheng, Paul Andrewes, Luke Yip, Gerald F. O'Malley, Richard M. Maiorino, Wayne Van Voorhies, Sheila M. Healy, Allison Titcomb, DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMAIII), excreted in human urine. Toxicology and Applied Pharmacology. ,vol. 165, pp. 74- 83 ,(2000) , 10.1006/TAAP.2000.8922
Dean E. Carter, Marjorie A. Peraza, Felix Ayala-Fierro, Elizabeth Casarez, David S. Barber, Shannon L. Winski, Arsenic Metabolism After Pulmonary Exposure Arsenic Exposure and Health Effects III#R##N#Proceedings of the Third International Conference on Arsenic Exposure and Health Effects, July 12–15, 1998, San Diego, California. pp. 299- 309 ,(1999) , 10.1016/B978-008043648-7/50034-0
M. Edraki, A. M. Lechner, V. Glenn, D. Mulligan, C. Unger, Mapping and Prioritising Rehabilitation of Abandoned Mines in Australia Life of Mine Conference (AusIMM). pp. 259- 266 ,(2012)
G M Kannan, S J S Flora, Smrati Bhadauria, Nutan Singh, Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review. Journal of Environmental Biology. ,vol. 28, pp. 333- 347 ,(2007)
R. Schulin, M. Megharaj, Kirk T. Semple, B. E. Clothier, R. Naidu, A. L. Juhasz, N. S. Bolan, S. K. Gupta, Bioavailability : definition, assessment and implications for risk assessment. Elsevier. ,(2008)
N. R. Labiris, M. B. Dolovich, Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications British Journal of Clinical Pharmacology. ,vol. 56, pp. 588- 599 ,(2003) , 10.1046/J.1365-2125.2003.01892.X
H Vasken Aposhian, Robert A Zakharyan, Mihaela D Avram, Adriana Sampayo-Reyes, Michael L Wollenberg, A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species. Toxicology and Applied Pharmacology. ,vol. 198, pp. 327- 335 ,(2004) , 10.1016/J.TAAP.2003.10.027
M. K. Ghose, S. R. Majee, Assessment of dust generation due to opencast coal mining - an Indian case study. Environmental Monitoring and Assessment. ,vol. 61, pp. 255- 263 ,(2000) , 10.1023/A:1006127407401