Analytical Methods for Characterization of Bile Acids and Its Application in Quality Control of Cow-Bezoar and Bear Bile Powder

摘要: Bile acids as characteristic compounds of human and animal bile are major endogenous products cholesterol play very important roles in homeostasis, lipid absorption production flow. At present, useful biomarkers signaling molecules for the diagnosis or treatment many diseases clinic. Various analytical methods, from overall to individual, qualitative quantitative, have been developed determination biomedical samples even bile-based medicinal materials. The most precious commonly-used traditional medicines cow-bezoar (CB) bear powder (BBP), which regard main bioactive constituents extensive use treating since thousands years ago. However, consumption CB BBP make their natural resource scarcity price valuableness. Currently, artificial, in-vitro cultured substitutes worse adulterants counterfeits mix medicine market they seriously compromised therapeutic effects these two medicines. To guarantee long-term development ethnodrugs, approaches utilized quality control BBP. In this paper, various methods summarized compared with each other.