Synthesis and antiarthritic study of a new orally active diferuloyl methane (curcumin) gold complex

摘要: Abstract Gold(I) complex of composition [AuL 2 ]Cl with diferuloyl methane (Curcumin) has been synthesised and characterised by elemental analysis, magnetic moment, IR electronic spectral studies. Antiarthritic studies on rats were also carried out using three parameters: (1) assessment remission in adjuvant induced polyarthritis assessed measurement paw volume, (2) X-ray to see the anatomical changes affected limb, (3) serum acid phosphatase level during disease course. The gold levels determined at different dose levels.