Syntheses, characterization and biological activities of rare earth metal complexes with curcumin and 1,10-phenanthroline-5,6-dione

摘要: Abstract Three new solid complexes have been synthesized by the reaction of rare earth(III) nitrate with first ligand curcumin (HL) and second 1,10-phenanthroline-5,6-dione (L′) in alcohol solution (pH = 6.5–7.0). The composition has characterized elemental analysis, molar conductivity, thermogravimetric IR, UV–vis methods. results reveal that β-diketone group to coordinates earth ions bidentate mode after deprotonated. But uses its two N atoms mode. general formula is REL 3 L′ (RE = Sm, Eu, Dy). antibacterial activity indicated excellent ability for testing bacterium than curcumin. result agarose gel electrophoresis suggested complex SmL can cleave plasmid DNA at physiological pH temperature. And it was found cleavage process sensitive pH, however, adding radical scavengers almost had no effect on reaction, therefore, does not produce diffusible hydroxyl radicals via Fenton reaction.