Biocoated piezoelectric biosensor platform for point-of-care diagnostic use

摘要: Biosensor components (chips )are described based on direct biocoating processes that result in the tenacious and stable, noncovalent (believed to be chemisorptive) binding of anchor substances such as avidin(s) other proteins having specific partners or oligo- poly-nucleotides onto any piezoelectrically active crystal surface. The resulting platform technology can developed for a variety biosensors with applications biological assays. table monolayers forms reactive layers, ready bind capture reagent biotinylated antibody detection analytes biologic fluid samples. Although herein performed type piezoelectric material number configurations, some embodiments are directed biosensor foregoing particular acoustic plate mode where interdigitated transducers (IDTs) present opposite side crystal's biocoated film.