Polypeptides having a single covalently bound n-terminal water-soluble polymer

作者: Sunitha Menon-Rudolph , Pradip Ghosh-Dastidar , Ziping Wei

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摘要: This invention provides compositions consisting essentially of a polypeptide and water-soluble polymer covalently bound thereto at the N-terminal α-carbon atom via hydrazone or reduced bond, an oxime bond. also methods making instant compositions, pharmaceutical comprising same, kits for use in preparing same.

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