Methods and compositions using kloto-fgf fusion polypeptides
作者： David Glass , Shou-Ih Hu
DOI:
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摘要: The present invention is directed to methods, kits and compositions for preventing or treating age-related conditions metabolic disorders. Klotho fusion polypeptides of the include at least a protein an active fragment thereof. In one embodiment, polypeptide comprises polypeptide, FGF (such as FGF23) (optionally) modified Fc fragment. can, example, have decreased binding Fc-gamma-receptor increased serum half-life. proteins are useful in treatment prevention variety another
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