Methods and compositions using klotho-fgf fusion polypeptides

作者: David Glass , Shou-Ih Hu

DOI:

关键词: Fusion proteinFibroblast growth factorChemistryImmunologyKlothoFusionBiochemistry

摘要: The present invention is directed to methods, kits and compositions for preventing or treating age-related conditions metabolic disorders. Klotho fusion polypeptides of the include at least a protein an active fragment thereof. proteins are useful in treatment preventionofa variety

参考文章(60)
John L.R. Rubenstein, Maike Sander, Roger A. Pedersen, Michael S. German, Juanito J. Meneses, Lori Sussel, Dennis J. Hartigan-O'Connor, NKX-2.2 and NKX-6.1 transgenic mouse models for diabetes, depression, and obesity ,(1997)
George Higgins, Apple tree -- Higred cultivar ,(1986)
Bradford A. Jameson, Robert K. Campbell, Scott C. Chappel, DNA encoding a hybrid heterodimeric protein ,(1997)
Makoto Kuroo, Youichi Nabeshima, Susumu Sekine, Akihiro Iida, Novel peptide, novel dna, and novel antibody ,(1997)
Sue C. Bodine, David J. Glass, Novel nucleic acid and polypeptide molecules ,(2002)
Liselotte Bjerre Knudsen, Søren Bregenholt, Carsten Foged Godtfredsen, Richard David Carr, Jacob Sten Petersen, Inhibition of beta cell degeneration ,(2000)
Michael Econs, Thomas Meitinger, Tim Matthias Strom, Ken White, Fibroblast growth factor (FGF23) nucleic acids ,(2001)