Transdifferentiation of ocular tissues in larval Xenopus laevis

摘要: Abstract Transdifferentiation phenomena offer a useful opportunity to study experimentally the mechanisms on which cell phenotypic stability depends. The capacities of vertebrate eye tissues reprogram differentiation are well known in avian and mammalian embryos, larval adult newt. From research into capacity anuran new pathway, considerable data have accumulated concerning trans-differentiative Xenopus laevis . This work reviews transdifferentiative that species and, based these, aims establish extent our knowledge about mechanism controlling these processes. In outer cornea can regenerate lens by lens-transdifferentiation process triggered sub-stained factor(s), probably protein nature, produced neural retina. normal is guaranteed presence inner lens, prevent spread retinal factor(s). stimulus for transdifferentiation be supplied other as well, but this not widely distributed. iris pigmented epithelium transdifferentiate retina if isolated from surrounding implanted vitreous chamber. As cornea, stimulated certain nonocular well.