Identification and semi-quantitative analysis of parabens and UV filters in cosmetic products by direct-analysis-in-real-time mass spectrometry and gas chromatography with mass spectrometric detection

摘要: A method based on direct-analysis-in-real-time mass spectrometry (DART-MS) for the qualitative and semi-quantitative analysis of eight organic UV filters four parabens in twelve cosmetic products with substantially different formulations (as cream, milk, lotion, oil, lipstick) was developed. All tested substances could be identified unambiguously investigated samples without any sample pre-treatment. Direct allows determination parabens. For no satisfactory results were obtained by direct but all analytes quantified simply dissolving methanol, addition an internal standard subsequent measurement solution DART-MS further The using confirmed a more established namely gas chromatography spectrometric detection (GC-MS).