Delayed gadolinium-enhanced magnetic resonance imaging of cartilage: Clinical associations in obese adults
作者： ANANTHILA ANANDACOOMARASAMY , BRUNO M. GIUFFRE , STEVEN LEIBMAN , IAN D. CATERSON , GARETT S. SMITH
关键词:
摘要: Objective. Delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) is used to assess glycosaminoglycan distribution. Our aim was determine the relationships between self-reported pain and disability, clinical variables, serum leptin, dGEMRIC indices in obese subjects with without knee osteoarthritis (OA). Methods. Seventy-seven were recruited from laparoscopic adjustable gastric banding or exercise diet-weight loss programs. The index assessed on MRI according established protocol. Regression analysis adjusted for age, sex, body mass (BMI), presence OA. Results. Mean age BMI 51 ± 12.7 years 39.6 6.2 kg/m 2 . Twenty-three (30%) had OA (American College Rheumatology criteria). medial lateral 538 80 ms 539 86 ms. Age correlated negatively (r = −0.40, p Conclusion. In subjects, associated OA, abnormal tibiofemoral alignment, quadriceps strength. Longitudinal studies are required potential improvement interventions such as strength training.
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