CITRATE AND THE CONVERSION OF CARBOHYDATE INTO FAT. ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF NORMAL AND DIABETIC RATS

摘要: 1. The activity of citrate-cleavage enzyme declines in alloxan-diabetes. 2. administration insulin elevates the livers normal and diabetic animals. Diets high glucose or fructose elevate animals, whereas only diet does so These observations parallel effects insulin, on fatty acid synthesis effect is brought into play more rapidly larger than glucose. 3. With one exception acetate thiokinase shows similar changes at a lower level activity. 4. results indicate that acts by increasing utilization, not exerting direct thiokinase.