Current and future drug-eluting coronary stent technology
作者： Alfonso Ielasi , Azeem Latib , Antonio Colombo
DOI: 10.1586/ERC.11.5
关键词:
摘要: Despite the impressive benefits obtained following introduction of drug-eluting stent, safety concerns have been raised over their long-term with particular regard to stent thrombosis. Various mechanisms such as delayed endothelialization, local hypersensitivity and endothelial dysfunction owing durable polymer coating and/or drug itself suggested possible causes this phenomenon. Therefore, address these concerns, a newer-generation stents has developed they are currently undergoing preclinical clinical evaluation in order increase both biocompatibility by optimizing three major components stents: platform, drug. This article critically reviews key trials current status new coronary devices well preventing future perspectives for continued development.
elsevier.com
expert-reviews.com参考文章(82)
Giora Weisz, Martin B. Leon, David R. Holmes, Dean J. Kereiakes, Jeffrey J. Popma, Paul S. Teirstein, Sidney A. Cohen, Hong Wang, Donald E. Cutlip, Jeffrey W. Moses, Five-year follow up after sirolimus-eluting stent implantation results of the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native Coronary Lesions) Trial Journal of the American College of Cardiology. ,vol. 53, pp. 1488- 1497 ,(2009) , 10.1016/J.JACC.2009.01.050
Chaim Lotan, Ian T. Meredith, Laura Mauri, Minglei Liu, Martin T. Rothman, Safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: 12-month data from the E-Five registry. Jacc-cardiovascular Interventions. ,vol. 2, pp. 1227- 1235 ,(2009) , 10.1016/J.JCIN.2009.10.001
Amnon Peled, Orit Kollet, Tanya Ponomaryov, Isabelle Petit, Suzanna Franitza, Valentin Grabovsky, Michal Magid Slav, Arnon Nagler, Ofer Lider, Ronen Alon, Dov Zipori, Tsvee Lapidot, The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood. ,vol. 95, pp. 3289- 3296 ,(2000) , 10.1182/BLOOD.V95.11.3289
Scot Garg, Patrick W. Serruys, Coronary Stents: Looking Forward Journal of the American College of Cardiology. ,vol. 56, ,(2010) , 10.1016/J.JACC.2010.06.008
Tom Adriaenssens, Julinda Mehilli, Rainer Wessely, Gjin Ndrepepa, Melchior Seyfarth, Anna Wieczorek, Birgit Blaich, Raisuke Iijima, Jürgen Pache, Adnan Kastrati, Albert Schömig, Does Addition of Estradiol Improve the Efficacy of a Rapamycin-Eluting Stent?: Results of the ISAR-PEACE Randomized Trial Journal of the American College of Cardiology. ,vol. 49, pp. 1265- 1271 ,(2007) , 10.1016/J.JACC.2007.02.021
Robert Whitbourn, Donald Cutlip, Jeffrey Popma, Peter Fitzgerald, Stephen Worthley, Darren Walters, Ian Meredith, The next-generation Endeavor Resolute stent: 4-month clinical and angiographic results from the Endeavor Resolute first-in-man trial. Eurointervention. ,vol. 3, pp. 50- 53 ,(2007) , 10.4244/EIJV3I1A08
Yaling Han, Quanmin Jing, Bo Xu, Lixia Yang, Huiliang Liu, Xiaoming Shang, Tieming Jiang, Zhanquan Li, Hua Zhang, Hui Li, Jian Qiu, Yingfeng Liu, Yi Li, Xuezhi Chen, Runlin Gao, Safety and Efficacy of Biodegradable Polymer-Coated Sirolimus-Eluting Stents in “Real-World” Practice JACC: Cardiovascular Interventions. ,vol. 2, pp. 303- 309 ,(2009) , 10.1016/J.JCIN.2008.12.013
Elena Ladich, Gaku Nakazawa, Renu Virmani, Aloke V Finn, Pathophysiology of vascular healing and stent mediated arterial injury. Eurointervention. ,vol. 4, ,(2008)
Patrick W Serruys, Peter Ruygrok, Jorg Neuzner, Jan J Piek, Ashok Seth, Joachim J Schofer, Gert Richardt, Marcus Wiemer, Didier Carrie, Leif Thuesen, Els Boone, Karine Miquel-Herbert, Joost Daemen, A randomised comparison of an everolimus-eluting coronary stent with a paclitaxel-eluting coronary stent:the SPIRIT II trial. Eurointervention. ,vol. 2, pp. 286- 294 ,(2006)
J. Ribamar Costa, Galo Maldonado, Alexandre Abizaid, Rodolfo Staico, Ricardo Costa, Dimytri Siqueira, Fausto Feres, Amanda G.M.R. Sousa, Luiz Fernando Tanajura, Raoul Bonan, J. Eduardo Sousa, Andréa Abizaid, 1-Year Results of the Hydroxyapatite Polymer-Free Sirolimus-Eluting Stent for the Treatment of Single De Novo Coronary Lesions JACC: Cardiovascular Interventions. ,vol. 2, pp. 422- 427 ,(2009) , 10.1016/J.JCIN.2009.02.009