Analyzing patterns of drug use in clinical notes for patient safety.

摘要: Doctors prescribe drugs for indications that are not FDA approved. Research indicates 21% of prescriptions filled off-label indications. Of those, more than 73% lack supporting scientific evidence. Traditional drug safety alerts may cover usages Therefore, analyzing patterns usage in the clinical setting is an important step toward reducing incidence adverse events and improving patient safety. We applied term extraction tools on notes a million patients to compile database statistically significant use. validated some learned from data against sources known on-label Given our ability quantify event risks using notes, this will enable us address because we can now rank-order use prioritize search their profiles.