The Genetics of Human Obesity
作者： Claude Bouchard , Louis P��russe
关键词:
摘要: This chapter summarizes the research on role of genetic variation in human obesity. It provides a brief review our current understanding level heritability and familial risk for increasing levels excess body weight. Single-gene defects known to cause obesity are discussed. The results large number association studies performed with candidate genes described. at least five positive highlighted. All published genomic scan relevant reviewed, an emphasis linkage characterized by apparent convergence two cohorts. Finally, gene–environment interactions response chronic or negative energy balance is examined. Keywords: candidate genes; energy balance; gene–environment interactions; genetics; genomic scan; molecular markers; obesity; quantitative trait locus
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