Antiepileptic drug withdrawal in childhood: does the duration of tapering off matter for seizure recurrence?
作者： Jessica Guerra Serra , Maria Augusta Montenegro , Marilisa M. Guerreiro
DOI: 10.1177/08830738050200071901
关键词:
摘要: There is no consensus on how long the duration of antiepileptic drug withdrawal after seizure control should be. The objective present study was to verify if tapering off matters for recurrence in children with controlled epilepsy. In this prospective study, patients were randomized taper during a period 1 or 6 months. Fifty-seven met inclusion criteria; 24 girls, and ages ranged from 2 16 years (mean 9.45 years). difference between two groups according age, gender, type epileptic syndrome, electroencephalogram abnormality, (P > .05). 1-month group, recurred 10 patients, as opposed 12 6-month group. analysis each group showed We conclude that does not influence risk childhood. (J Child Neurol 2005;20:624—626).
sagepub.com
sci-hub.se 参考文章(21)
Kenji Kushima, Yutaka Satoh, Yoshio Ban, Matsuo Taniyama, Kunihiko Ito, Koujiro Sugita, Graves' thyrotoxicosis and Moyamoya disease. Canadian Journal of Neurological Sciences. ,vol. 18, pp. 140- 142 ,(1991) , 10.1017/S0317167100031607
A.C.B. Peters, O. F. Brouwer, A. T. Geerts, W. F.M. Arts, H. Stroink, C. A. van Donselaar, Randomized prospective study of early discontinuation of antiepileptic drugs in children with epilepsy. Neurology. ,vol. 50, pp. 724- 730 ,(1998) , 10.1212/WNL.50.3.724
W. F. M. Arts, L. H. Visser, M. C. B. Loonen, A. T. Tjiam, H. Stroink, P. M. Stuurmany, D. C. J. Poortvliet, Follow-up of 146 children with epilepsy after withdrawal of antiepileptic therapy. Epilepsia. ,vol. 29, pp. 244- 250 ,(1988) , 10.1111/J.1528-1157.1988.TB03713.X
Maria Matricardi, Mario Brinciotti, Pietro Benedetti, Outcome After Discontinuation of Antiepileptic Drug Therapy in Children with Epilepsy Epilepsia. ,vol. 30, pp. 582- 589 ,(1989) , 10.1111/J.1528-1157.1989.TB05476.X
Jose Luiz D. Gherpelli, Fernando Kok, Silvana dal Forno, Livia C. Elkis, Beatriz H. W. Lefevre, Aron J. Diament, Discontinuing medication in epileptic children : a study of risk factors related to recurrence Epilepsia. ,vol. 33, pp. 681- 686 ,(1992) , 10.1111/J.1528-1157.1992.TB02347.X
P A Bouma, A C Peters, R J Arts, T Stijnen, J Van Rossum, Discontinuation of antiepileptic therapy: a prospective study in children. Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 50, pp. 1579- 1583 ,(1987) , 10.1136/JNNP.50.12.1579
Steven C. Cramer, Richard L. Robertson, Elizabeth C. Dooling, R. Michael Scott, Moyamoya and Down Syndrome Clinical and Radiological Features Stroke. ,vol. 27, pp. 2131- 2135 ,(1996) , 10.1161/01.STR.27.11.2131
Mizuho Horikawa, Hidetuna Utunomiya, Seki Hirotaka, Shuji Yamada, Etsuo Ohtaki, Toyojiro Matsuishi, CASE OF VON RECKLINGHAUSEN DISEASE ASSOCIATED WITH CEREBRAL INFARCTION Journal of Child Neurology. ,vol. 12, pp. 144- 146 ,(1997) , 10.1177/088307389701200213
J. Dooley, K. Gordon, P. Camfield, C. Camfield, E. Smith, Discontinuation of anticonvulsant therapy in children free of seizures for 1 year A prospective study Neurology. ,vol. 46, pp. 969- 974 ,(1996) , 10.1212/WNL.46.4.969
Robert S. Greenwood, Michael B. Tennison, When to start and stop anticonvulsant therapy in children. JAMA Neurology. ,vol. 56, pp. 1073- 1077 ,(1999) , 10.1001/ARCHNEUR.56.9.1073