Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics

作者: SALLY E. WENZEL , LAWRENCE B. SCHWARTZ , ESTHER L. LANGMACK , JANET L. HALLIDAY , JOHN B. TRUDEAU

DOI: 10.1164/AJRCCM.160.3.9812110

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摘要: The mechanisms associated with the development of severe, corticosteroid (CS)-dependent asthma are poorly understood, but likely heterogenous. It was hypothesized that severe …

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