Clinical Expression of Precocious Puberty in Girls

摘要: Premature development of breast and/or pubic hair in a prepubertal girl used to raise questions and concerns from the families. There is actually wide range clinical expressions precocious puberty girls not all presentations are considered be true puberty. Central occurs 10–20% girls, but beside typical forms other have been identified. In 50–60% cases, only one secondary sex characteristic shows premature raises diagnosis thelarche, pubarche or isolated metrorrhagia. 10% autonomous ovarian overproduction estrogens causes peripheral Lastly, hyperestrogenism may exogenous causes, such as exposure environmental chemical pollutants. A decision on therapeutic management based clinical, biological radiologic examinations, LHRH analogous treatment should limited central before age 8 years.