Arterial stiffness and central hemodynamics in treated hypertensive subjects according to brachial blood pressure classification.

摘要: Background International recommendations have classified brachial blood pressure (BP) in subgroups enabling better cardiovascular risk stratification. Central BP is an independent predictor of risk, differing from through the predominant influence arterial stiffness and wave reflections. has never been studied relation to international guidelines for classification. Methods In 580 chronically treated hypertensive subjects we measured: carotid–femoral pulse velocity (PWV), carotid artery augmentation index (AI) pressures, using applanation tonometry analysis, calibration. Results For each given value, systolic (SBP) PP were significantly lower than corresponding SBP PP. This amplification was ‘optimal’ ‘normal’ ranges (6.8–7.4 mmHg) higher (10.1–11.3 mmHg), mainly depending on heart rate (HR) PWV levels. gradually increased as a function classification significant this independently age, drug treatment, atherosclerotic lesions even mean BP. Finally, highly sensitive marker effective control throughout all decades age. Conclusion Under chronic antihypertensive therapy, central does not strictly parallel classification, differences aortic HR. Whether might predict and/or presence control, suggested study, needs further confirmation.