Impact of alcohol intoxication on hemodynamic, metabolic, and cytokine responses to hemorrhagic shock.

作者: Herbert Phelan , Paul Stahls , John Hunt , Gregory J. Bagby , Patricia E. Molina

DOI: 10.1097/00005373-200204000-00010

关键词:

摘要: Background Alcohol intoxication is associated with a high incidence of traumatic injury, particularly in the young healthy population. The impact alcohol on immediate pathophysiologic response to injury has not been closely examined. We hypothesized that acute intoxicatio

参考文章(39)
Kelly A.N Messingham, Christine V Fontanilla, Alessandra Colantoni, Lisa A Duffner, Elizabeth J Kovacs, Cellular immunity after ethanol exposure and burn injury: dose and time dependence. Alcohol. ,vol. 22, pp. 35- 44 ,(2000) , 10.1016/S0741-8329(00)00100-2
T. V. Berne, H. Belzberg, G. Velmahos, J. A. Asensio, Demetrios Demetriades, L. S. Chan, D. Chan, D. Kahaku, B. M. Stewart, E. E. Cornwell, D. B. Oder, The prevalence and effect of alcohol and drug abuse on cohort-matched critically injured patients. American Surgeon. ,vol. 64, pp. 461- 465 ,(1998)
Patricia E. Molina, Sayeed Malek, Charles H. Lang, Luping Qian, Rebecca Naukam, Naji N. Abumrad, Early organ-specific hemorrhage-induced increases in tissue cytokine content: associated neurohormonal and opioid alterations. Neuroimmunomodulation. ,vol. 4, pp. 28- 36 ,(1997) , 10.1159/000097312
Saman Arbabi, Ronald V. Maier, Iris Garcia, Gregory J. Bauer, Alcohol (Ethanol) Inhibits IL-8 and TNF: Role of the p38 Pathway Journal of Immunology. ,vol. 162, pp. 7441- 7445 ,(1999)
D J Brackett, M R Lerner, M F Wilson, F A Holloway, D V Gauvin, Dose- and time-dependent cardiovascular responses induced by ethanol. Journal of Pharmacology and Experimental Therapeutics. ,vol. 268, pp. 78- 84 ,(1994)
R Shenkar, W F Coulson, E Abraham, Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury. American Journal of Respiratory Cell and Molecular Biology. ,vol. 10, pp. 290- 297 ,(1994) , 10.1165/AJRCMB.10.3.8117448
JAMES W. DAVIS, STEVEN R. SHACKFORD, ROBERT C. MACKERSIE, DAVID B. HOYT, Base deficit as a guide to volume resuscitation. Journal of Trauma-injury Infection and Critical Care. ,vol. 28, pp. 1464- 1467 ,(1988) , 10.1097/00005373-198810000-00010
Ping Wang, Zheng F. Ba, Andrew Biondo, Irshad H. Chaudry, Liver endothelial cell dysfunction occurs early following hemorrhagic shock and persists despite crystalloid resuscitation. Journal of Surgical Research. ,vol. 63, pp. 241- 247 ,(1996) , 10.1006/JSRE.1996.0255
Anil Gulati, Rikhab C. Srimal, Hemendra N. Bhargava, Effect of varying concentration of ethanol on systemic hemodynamics and regional circulation. Alcohol. ,vol. 6, pp. 9- 15 ,(1989) , 10.1016/0741-8329(89)90067-0