Pyrazolopyridine derivatives as selective cox-2 inhibitors
作者： Alan Glaxo Wellcome plc Naylor , Ian Baxter Glaxo Wellcome plc Campbell
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摘要: The invention provides the compounds of formula (I) and pharmaceutically acceptable derivatives thereof in which : R?0 R1? are independently selected from H, halogen, C?1-6?alkyl, C1-6alkoxy, or C1-6alkoxy substituted by one more fluorine atoms; R?2? is C1-6alkyl atoms, C1-6hydroxyalkyl, SC1-6alkyl, C(O)H, C(O)C1-6alkyl, C1-6alkylsulphonyl, R?3? C?1-6?alkyl NH2. Compounds potent selective inhibitors COX-2 use treatment pain, fever, inflammation a variety conditions diseases.
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