作者: William Insull , R. W. Jeffery , A. P. Boyar , D. W. Nixon , E. H. Asp
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摘要: A multicentered pilot study was conducted to test an intervention protocol designed reduce fat intake 15% of energy intake. Eligible subjects were postmenopausal women with stage II breast cancer whose baseline more than 30% The low-fat diet consisted bi-weekly individual counseling sessions emphasis on substitution lower-fat foods for high-fat and maintenance nutritional adequacy. Nutrient intakes calculated from 4-day food records collected at after 3 months intervention. Mean daily the 17 patients dropped significantly 38.4 +/- 4.3% 22.8 7.8% (p less .001). 25% reduction in mean intake, 1,840 419 kcal 1,365 291 months, accompanied by significant increases protein carbohydrate as percent weight loss 2.8 kg a 7.7% serum cholesterol observed; both changes p .01 level. Absolute zinc magnesium reduced. However, 14 vitamins minerals, including magnesium, exceeded two-thirds 1989 Recommended Dietary Allowances (RDAs). When expressed nutrient density (i.e., amount per 1,000 kcal), observed all micronutrients. These results support hypothesis that nutritionally adequate can be successfully implemented highly motivated, free-living population.