Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomy

摘要: Background Pancreatic fistula (PF) after pancreatoduodenectomy (PD) remains a challenging problem. The only commonly accepted risk factor is the soft consistency of pancreatic remnant. Methods In all, 100 consecutive patients underwent PD. All data, including factors for PF and defined according to International Study Group Fistula, were collected prospectively. On margin, score fibrosis fatty infiltration assessed by pathologist blinded postoperative course. Results occurred in 31% patients. univariate analysis, male sex, age greater than 58 years, body mass index (BMI) ≥25 kg/m 2 , pre-operative high blood pressure, operation nonintraductal papillary mucinous neoplasm (IPMN) disease ampullary carcinoma, operative time, loss, remnant, absence fibrosis, presence pancreas associated with PF. multivariate BMI ≥25kg/m significant predictors A based on number present divided patient population into 4 subgroups carrying that ranged from 7% (no factor) 78% (3 factors) 0% 81%, taking account symptomatic (grade B C). Conclusion an increased BMI, pancreas, as allows more precise objective prediction remnant alone. predictive these 3 could help tailor preventive measures.