Primarily resectable pancreatic adenocarcinoma - to operate or to refer the patient to an oncologist?

摘要: The aim of this work is to investigate the optimal therapeutic sequence resectable pancreatic cancer - primary surgery with adjuvant therapy or neoadjuvant followed by resection. Application approach in routine treatment rapidly growing every year, despite lack final results from randomized trials. Recent advancements therapy, due more effective chemotherapy regimens, favor upfront strategy. On other hand, theoretical background and metaanalyses Currently, resection remains standard cancer, but first recommendations considering as an option seem arise among scientific societies a global impact. Preliminary Prodige 24 study PREOPANC-1 trial demonstrates that both options are worth further evaluation clinical Their should soon provide answers important questions.