Hypercalcemia of Malignancy in a Dog Diagnosed With Cholangiocellular Carcinoma

摘要: Abstract A 4-year-old, neutered male Golden Retriever was presented with a 1-week history of weight loss, polyuria, and polydipsia. The diagnostic workup showed an increased ionized calcium concentration, mild increase in serum creatinine urea severe hyperlipasemia. complete abdominal ultrasound revealed multiple hepatic nodules. cytological diagnosis malignant epithelial neoplasia, highly suggestive bile duct adenocarcinoma made. In order to confirm the presumptive hypercalcemia malignancy due presence parathormone-related peptide concentration measured, result concentration. dog hospitalized received supportive treatments consisting intravenous furosemide fluid therapy. After ruling out lymphoma hypoadrenocorticism, oral prednisone initiated decreased gradually down normal after 7 days hospitalization. Chemotherapy epirubicin based on diagnosis. One month worsening its clinical condition, humanely euthanized. Postmortem examination confirmed cholangiocellular carcinoma. To our knowledge, this is first report associated carcinoma dog.