Embryonal rhabdomyosarcoma of the orbit in a liver transplant recipient

摘要: Although an increased incidence of de novo malignancies is reported in transplant recipients, rhabdomyosarcoma, aggressive mesenchymal tumor typical childhood, not considered a neoplasm commonly related to immunosuppression. A 21-year-old woman presented with unilateral diplopia and proptosis 16 months after liver transplantation for fulminant hepatic failure. tumoral mass originating from the medial rectus muscle was partially removed diagnosed as being embryonal rhabdomyosarcoma. Since patient refused complete orbital excision, one course radiotherapy six courses chemotherapy were administered, while immunosuppression re-modulated, without interruption administration cyclosporine. Complete control growth achieved, no alterations graft function observed throughout treatment period.