Pharmaceutical composition comprising modified hemoglobin-based therapeutic agent for cancer targeting treatment and diagnostic imaging

摘要: The present invention provides a pharmaceutical composition containing hemoglobin-based therapeutic agent for treating cancer. hemoglobin moiety can target cancer cells and the (i.e. active agent/therapeutic drug) kill efficiently. used in be treatment of various cancers such as pancreatic cancer, leukemia, head neck colorectal lung breast liver nasopharyngeal esophageal prostate stomach brain alone or combination with other agent(s) chemotherapeutic to give synergistic effect on treatment, inhibiting metastasis and/or reducing recurrence. presently claimed 5FU-two-dye conjugate 5FU-one-dye also live-cell imaging diagnostic imaging.