Recent advances in transition metal-catalyzed enantioselective hydrogenation of unprotected enamines

摘要: Transition metal-catalyzed enantioselective hydrogenation of enamines is undoubtedly a useful and environment-friendly method for the preparation optically pure chiral amines amine derivatives. Over last few decades, use transition metal catalysts containing phosphorus or phosphine–oxazoline ligands attracted much attention unprotected enamines. A number efficient have been developed, some them shown high potential application in synthesis optical both laboratory industry. This tutorial review focuses on contributions concerning