An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex.
作者： Tien An Nguyen , Benguo Liu , Jian Zhao , Donald S. Thomas , James M. Hook
DOI: 10.1016/J.FOODCHEM.2012.07.104
关键词:
摘要: The formation of supramolecular inclusion complexes between rutin and four cyclodextrins, namely β-cyclodextrin (β-CD), (2-hydroxypropyl)-α-cyclodextrin (HP-α-CD), (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD) (2-hydroxypropyl)-γ-cyclodextrin (HP-γ-CD), the effects complexation on stability antioxidant activity were investigated. Results from phase-solubility studies showed that formed 1:1 stoichiometric with HP-α-CD, β-CD, HP-β-CD HP-γ-CD; HP-γ-CD had greatest constants, followed by β-CD HP-α-CD. Thermodynamic demonstrate into was an exothermic process which occurred spontaneously. Two-dimensional rotating-frame nuclear Overhauser effect spectroscopy (2D ROESY) (1)H NMR analyses show A ring part molecule most likely inserted cavity HP-β-CD, thus forming a complex. Formation such complex conferred moderate degrees protection to degradation heat UV radiation during storage, significantly enhanced its capacity as determined three different procedures.
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