Role of Apple Phytochemicals, Phloretin and Phloridzin, in Modulating Processes Related to Intestinal Inflammation.
作者： Danuta Zielinska , José Moisés Laparra-Llopis , Henryk Zielinski , Dorota Szawara-Nowak , Juan Antonio Giménez-Bastida
DOI: 10.3390/NU11051173
关键词:
摘要: Plant-derived food consumption has gained attention as potential intervention for the improvement of intestinal inflammatory diseases. Apple consumption has been shown to be effective at ameliorating intestinal inflammation symptoms. These beneficial effects have been related to (poly) phenols, including phloretin (Phlor) and its glycoside named phloridzin (Phldz). To deepen the modulatory effects of these molecules we studied: i) their influence on the synthesis of proinflammatory molecules (PGE2, IL-8, IL-6, MCP-1, and …
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sci-hub.se 参考文章(59)
S L, B F, RELEVANCE OF APPLE POLYPHENOLS AS ANTIOXIDANTS IN HUMAN PLASMA: CONTRASTING IN VITRO AND IN VIVO EFFECTS Free Radical Biology and Medicine. ,vol. 36, pp. 201- 211 ,(2003) , 10.1016/J.FREERADBIOMED.2003.10.005
Iris F.F. Benzie, J.J. Strain, FERRIC REDUCING/ANTIOXIDANT POWER ASSAY: DIRECT MEASURE OF TOTAL ANTIOXIDANT ACTIVITY OF BIOLOGICAL FLUIDS AND MODIFIED VERSION FOR SIMULTANEOUS MEASUREMENT OF TOTAL ANTIOXIDANT POWER AND ASCORBIC ACID CONCENTRATION Methods in Enzymology. ,vol. 299, pp. 15- 27 ,(1999) , 10.1016/S0076-6879(99)99005-5
Vanessa Crespy, Olivier Aprikian, Christine Morand, Catherine Besson, Claudine Manach, Christian Demigné, Christian Rémésy, Bioavailability of Phloretin and Phloridzin in Rats Journal of Nutrition. ,vol. 131, pp. 3227- 3230 ,(2001) , 10.1093/JN/131.12.3227
Wen-Chung Huang, Shu-Ju Wu, Rong-Syuan Tu, You-Rong Lai, Chian-Jiun Liou, Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 expression through inhibition of MAPK, Akt, and NF-κB signaling in human lung epithelial cells. Food & Function. ,vol. 6, pp. 1960- 1967 ,(2015) , 10.1039/C5FO00149H
Jan Oszmiański, Michał Wolniak, Aneta Wojdyło, Iwona Wawer, Influence of apple purée preparation and storage on polyphenol contents and antioxidant activity Food Chemistry. ,vol. 107, pp. 1473- 1484 ,(2008) , 10.1016/J.FOODCHEM.2007.10.003
Xiaofang Peng, Jinyu Ma, Feng Chen, Mingfu Wang, Naturally occurring inhibitors against the formation of advanced glycation end-products Food & Function. ,vol. 2, pp. 289- 301 ,(2011) , 10.1039/C1FO10034C
M. Amzad Hossain, S.M. Salehuddin, M.J. Kabir, S.M.M. Rahman, H.P. Vasantha Rupasinghe, Sinensetin, rutin, 3′-hydroxy-5, 6, 7, 4′-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of the skin of apple fruit Food Chemistry. ,vol. 113, pp. 185- 190 ,(2009) , 10.1016/J.FOODCHEM.2008.07.085
Rong Tsao, Raymond Yang, J. Christopher Young, Honghui Zhu, Polyphenolic profiles in eight apple cultivars using high-performance liquid chromatography (HPLC). Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 6347- 6353 ,(2003) , 10.1021/JF0346298
Sandipan Chakraborty, Anait S Levenson, Pradip K Biswas, Structural insights into Resveratrol’s antagonist and partial agonist actions on estrogen receptor alpha BMC Structural Biology. ,vol. 13, pp. 27- 27 ,(2013) , 10.1186/1472-6807-13-27
Přemysl Mladěnka, Libuše Zatloukalová, Tomáš Filipský, Radomír Hrdina, Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity Free Radical Biology and Medicine. ,vol. 49, pp. 963- 975 ,(2010) , 10.1016/J.FREERADBIOMED.2010.06.010