Alkylation of δ-ketoesters : a mechanism change depending on conformational mobility and substituent effects on stereoselection.
作者： D. Di Maio , E. Vecchi , E. Zeuli
DOI: 10.1016/S0040-4039(00)85800-1
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摘要: Abstract Kinetic evidence shows that the two groups of a δ-ketoester can interact in transition state Grignard reaction. This promotes high stereoselectivity by chiral center far from ketonic group and produces good correlations between stereoselection electronic effects substituents.
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sci-hub.se 参考文章(3)
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