Genetic predisposition to bullous pemphigoid.
作者： Jieyu Zhang , Gang Wang
DOI: 10.1016/J.JDERMSCI.2020.05.010
关键词:
摘要: Bullous pemphigoid (BP) is a common autoimmune blistering skin disease that mainly affects elderly patients. Although BP risk is strongly influenced by age, genetic factors are also important determinants of this disease. Many genomic regions, especially in the HLA-II region, have been found to influence BP susceptibility through targeted sequencing studies. However, the relationship between non-HLA regions and BP susceptibility remains poorly understood and the identification of functional variants and key genes within these …
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