Carcinoid tumors of the duodenum and the ampulla of Vater: Current diagnostic and therapeutic approach in a series of 8 patients. Case series

摘要: Abstract Aim To describe the specific characteristics of duodenal/perivaterian carcinoids and to analyze diagnostic/therapeutic approach. Material methods Eight patients were included in our study. Symptoms on admission dyspepsia, upper gastrointestinal (GI) bleeding anemia. All underwent GI endoscopy peptides (gastrin) neuroendocrine markers (Chromogranin-A, CgA) measurement. Imaging studies performed all patients, including OCTREOSCAN, while with ACs MRCP or ERCP was also performed, when necessary. Definite diagnosis confirmed by histopathologic examination. Results Polypoid masses (carcinoids) revealed at duodenal bulb ampulla Vater, 5 3 respectively. Serum gastrin moderately increased 4 one patient it more than 1000 pg/ml. CgA patient, whom OCTREOSCAN detected a solitary hepatic metastasis. Two DC, less 1 cm diameter, treated endoscopic polypectomy, other surgery. The metastasis positive received Octreotide LAR, resulting stabilization disease. No recurrence metastases observed during follow-up (range : 1.5–9.6 years). Conclusions In DC tumors AC, surgical resection is treatment choice. metastatic tumors, primary lesion administration somatostatin analogues may stabilize disease improve patient's quality life.