Obesity, weight loss and conditional cardiovascular risk factors

作者: T. Tzotzas , P. Evangelou , D. N. Kiortsis

DOI: 10.1111/J.1467-789X.2010.00807.X

关键词:

摘要: Summary Obesity is a pathological condition aggregating substantial number of proatherogenic factors, such as insulin resistance, type 2 diabetes mellitus, dyslipidaemia and hypertension. In addition to these classic cardiometabolic risk atherosclerosis may be aggravated by other non-classic which are characterized conditional, including homocysteine, fibrinogen, lipoprotein(a), LDL particle size high-sensitivity CRP. Some biomarkers disturbed in obesity because combination dietary hypertrophic adipose tissue, low-grade inflammation, resistance parameters under investigation. For the reduction weight loss exceeding 10–20% initial body probably necessary, achieved through either conventional lifestyle measures or more drastic interventions bariatric surgery. It has been shown that certain well-balanced diets, Mediterranean diet, constitute means improving concerted manner levels CRP, homocysteine small dense particles, regardless loss. The significance considering factors management intervention an issue needs further

参考文章(83)
Beucler I, Kiortsis Dn, Giral P, Turpin G, Valsamides S, Bruckert E, Tzotzas T, Changes in lipoprotein(a) levels and hormonal correlations during a weight reduction program. Nutrition Metabolism and Cardiovascular Diseases. ,vol. 11, pp. 153- ,(2001)
Saris W, Cobbaert C, Kempen K, Muls E, Vansant G, The effects of weight loss and apolipoprotein E polymorphism on serum lipids, apolipoproteins A-I and B, and lipoprotein(a). International Journal of Obesity. ,vol. 17, pp. 711- 716 ,(1993)
Christina Chrysohoou, Demosthenes B Panagiotakos, Christos Pitsavos, Undurti N Das, Christodoulos Stefanadis, Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: The ATTICA Study. Journal of the American College of Cardiology. ,vol. 44, pp. 152- 158 ,(2004) , 10.1016/J.JACC.2004.03.039
A. Hernández-Mijares, D. Corella, F. España, A. Vayá, A. Estellés, E. Solá, M. Simó, C. Morillas, Fibrinogen, plasma viscosity and blood viscosity in obesity. Relationship with insulin resistance. Clinical Hemorheology and Microcirculation. ,vol. 37, pp. 309- 318 ,(2007)
James P Corsetti, Judith A Sterry, Janet D Sparks, Charles E Sparks, Michael Weintraub, Effect of weight loss on serum lipoprotein(a) concentrations in an obese population. Clinical Chemistry. ,vol. 37, pp. 1191- 1195 ,(1991) , 10.1093/CLINCHEM/37.7.1191
Ching-Jung Hsieh, Pei-Wen Wang, Rue-Tsuan Liu, Shih-Chen Tung, Wen-Yen Chien, Jung-Fu Chen, Chen-Hsiong Chen, Ming-Chun Kuo, Ya-Hui Hu, Orlistat for obesity: benefits beyond weight loss. Diabetes Research and Clinical Practice. ,vol. 67, pp. 78- 83 ,(2005) , 10.1016/J.DIABRES.2004.05.012
Themistoklis Tzotzas, Laure Dumont, Athanasios Triantos, Michael Karamouzis, Theodoros Constantinidis, Laurent Lagrost, Early decreases in plasma lipid transfer proteins during weight reduction. Obesity. ,vol. 14, pp. 1038- 1045 ,(2006) , 10.1038/OBY.2006.119
Maria Raitakari, Thomas Ilvonen, Markku Ahotupa, Terho Lehtimäki, Aimo Harmoinen, Pauli Suominen, Juhani Elo, Jaakko Hartiala, Olli T. Raitakari, Weight Reduction With Very-Low-Caloric Diet and Endothelial Function in Overweight Adults: Role of Plasma Glucose Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 24, pp. 124- 128 ,(2004) , 10.1161/01.ATV.0000109749.11042.7C
Lori Mosca, C-Reactive Protein — To Screen or Not to Screen? New England Journal of Medicine. ,vol. 347, pp. 1615- 1617 ,(2002) , 10.1056/NEJME020127