Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis

摘要: Acute pouchitis (AP) after ileal pouch-anal anastomosis (IPAA) is common and easily treated. However, chronic (CP) remains a difficult management problem may represent form of Crohn disease (CD) the pouch. Because CD patients have higher platelet counts than ulcerative colotis (UC) patients, we prospectively evaluated association between preoperative count development in 159 undergoing IPAA. Reactive thrombocytosis (RT) was defined as >450 x 10 9 /L. Median 312 /L (range, 103 to 886 /L). One hundred twenty-five (79%) had normal (150 450 /L) (-RT patient group). Twenty-eight (18%) RT. Six (3%) below 150 After median follow-up 13 months, 45 (28%) developed pouchitis. Pouchitis 33 +RT (26%) versus -RT (32%) (P = NS). UC who 25 per cent incidence CP compared only 7 those 0.03). The significantly IPAA having before surgery surgery.