作者: Christopher Rolfes , Stephen Howard , Ryan Goff , Paul A.
DOI: 10.5772/48577
关键词:
摘要: It is noteworthy to consider that extensive bioavailability and bioequivalence studies are typically required before new drug therapies can be approved [1]. These include pharmacokinetic take into account: 1) dosing, absorption, elimination rates of the its active metabolites, as well 2) potential effects multiple doses, interactions, differences whether medications taken with or without food. A major therapeutic factor compounds variations often seen from patient individual in absorption rates. This will also cause amount reaches desired targeted tissue when used a clinical therapy.