EFFECT OF PINEALECTOMY AND MELATONIN ON VASOPRESSIN-POTENTIATED PASSIVE AVOIDANCE IN RATS

摘要: The pineal indoleamine, melatonin, and the hypothalamic neuropeptide, vasopressin, facilitate passive avoidance behaviour in rats. similarity of effects suggest that interaction might occur between two substances. Therefore, effect intraperitoneally applied vasopressin and/or melatonin on one-trial learning was studied pinealectomized Intraperitoneal treatment with 500 ng 1 hr before retention test increased latency sham-operated In rats, an identical amount ineffective. blocked vasopressin. It is concluded needs a regulated function for developing behaviour.