Mild asthma: an expert review on epidemiology, clinical characteristics and treatment recommendations

作者: D. Dusser , D. Montani , P. Chanez , J. de Blic , C. Delacourt

DOI: 10.1111/J.1398-9995.2007.01394.X

关键词:

摘要: This review is the synthesis of a working group on mild asthma. Mild asthma includes intermittent and persistent according to Global Initiative for Asthma (GINA) classification, affects between 50% 75% asthmatic patients. more frequent, symptomatic, less well controlled in children than adults. Cohort studies from childhood adulthood show that severity usually remains stable over time. Nevertheless, can lead severe exacerbations, with frequency ranging 0.12 0.77 per patient-year. Severe exacerbations represent 30-40% requiring emergency consultation. In asthma, inflammation structural remodelling are constant, varying intensity, but nonspecific. Therapy inhaled corticosteroids (ICS) decreases bronchial inflammation, has only slight effect remodelling, and, when stopped, immediately recurs. Permanent low-dose ICS therapy reference treatment Effectiveness be reassessed at 3 months, if it insufficient patient no longer considered mildly asthmatic, stepped up. As most frequent form disease, diagnosis management require physicians' particular attention.

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