Efficacy of mometasone furoate and fluticasone furoate on persistent allergic rhinoconjunctivitis.

摘要: Allergic rhinoconjunctivitis denotes both nasal and ocular manifestation of allergy, which may be solely treated with intranasal steroid. This study compares the efficacy mometasone furoate spray (NS) fluticasone NS in treatment allergic rhinoconjunctivitis. The secondary objective is to severity baseline symptoms Seventy-eight patients were assessed subjectively objectively using twice-daily symptom scores for (reflective total score [rTNSS] instantaneous TNSS [iTNSS]) [rTOSS] TOSS [iTOSS]) symptoms, quality-of-life questionnaires (RQOLQs), acoustic rhinometry. All measurements taken at 4 8 weeks treatment. Sixty-three who randomized into group (n = 36) 27) completed study. Seventy-six percent had mild 20.5% moderate only 2.6% severe based on iTOSS; 65.1% 3% symptoms. There was significant reduction after 1 week (p < 0.05). Both groups improvement RQOLQ month, further improved 2 months dimensions also 0.05) but there no statistically difference between groups. are effective as single-modality majority manifest that steroids.