作者: Sriram Pothapregada , Banupriya Kamalakannan , Mahalaskhmy Thulasingham , Srinivasan Sampath
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摘要: Objective: To study the clinical profile and outcome of dengue fever in children at a tertiary care hospital Puducherry. Materials Methods: All (0-12 years age) diagnosed confirmed as from August 2012 to January 2015 were reviewed retrospectively case records per revised World Health Organization guidelines for fever. The diagnosis was by NS1 antigen-based ELISA test or serology IgM IgG antibodies, data analyzed using SPSS 16.0 statistical software. After collecting data, all variables summarized descriptive statistics. Results: Among 261 cases non-severe severe infection seen 60.9% 39.1%, respectively. mean age (standard deviation) presentation 6.9 + 3.3 male: female ratio 1.2:1. most common manifestations (94.6%), conjunctival congestion (89.6%), myalgia (81.9%), coryza (79.7%), headache (75.1%), palmar erythema (62.8%), retro-orbital pain (51.3%). early warning signs time admission persistent vomiting liver enlargement (59.8%), cold clammy extremities (45.2%), abdomen (31.0%), hypotension (29.5%), restlessness (26.4%), giddiness (23.0%), bleeding (19.9%), oliguria (18.4%). manifestation shock (39.1%), multi-organ dysfunction (2.3%). complications dysfunction, acute respiratory distress syndrome, encephalopathy, pleural effusion, ascites, myocarditis, myositis, kidney injury, disseminated intravascular coagulopathy. Platelet count did not always correlate well with severity bleeding. There six deaths (2.3%) out them four presented impaired consciousness (66.6%). causes poor multiorgan failure, fluid refractory shock. Conclusion: has been resurgence change pattern during recent epidemics. Clinical vigilance awareness regarding changing epidemic timely detection are vital reduce mortality morbidity due infection.