Genetics of Noninsulin-Dependent Diabetes Mellitus (NIDDM)
作者： Henning Beck-Nielsen , Allan Vaag , Kirsten Ohm Kyvik
DOI: 10.1007/978-1-4757-3906-0_6
关键词:
摘要: Noninsulin-dependent diabetes mellitus (NIDDM) or type II is a serious and fast-growing disease affecting about 5–10% of the adults in Western world (1). NIDDM preceded by impaired glucose tolerance (IGT), which affects 25% population over 50 yr age—a with nearly as high morbidity mortality rate NIDDM—despite “normal” fasting plasma values (2). Both IGT result 200–300% increased rates, mainly from myocardial infarction Therefore, syndrome—from early stages to fulminant hyperglycemic state—is challenge for all clinicians.
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J. P. Felber, Significance of the Randle-Mechanism in the etiology of diabetes type II. Hormone and metabolic research. Supplement series. ,vol. 22, pp. 11- 17 ,(1990)
T. I. A. Sørensen, A. J. Stunkard, Does obesity run in families because of genes? An adoption study using silhouettes as a measure of obesity. Acta Psychiatrica Scandinavica. ,vol. 87, pp. 67- 72 ,(1993) , 10.1111/J.1600-0447.1993.TB05363.X
Elisabeth Widén, Markku Lehto, Timo Kanninen, Jeremy Walston, Alan R. Shuldiner, Leif C. Groop, Association of a Polymorphism in the β3-Adrenergic–Receptor Gene with Features of the Insulin Resistance Syndrome in Finns New England Journal of Medicine. ,vol. 333, pp. 348- 352 ,(1995) , 10.1056/NEJM199508103330604
P. Z. Zimmet, The Pathogenesis and Prevention of Diabetes in Adults: Genes, autoimmunity, and demography Diabetes Care. ,vol. 18, pp. 1050- 1064 ,(1995) , 10.2337/DIACARE.18.7.1050
Ph. Froguel, M. Vaxillaire, F. Sun, G. Velho, H. Zouali, M. O. Butel, S. Lesage, N. Vionnet, K. Clément, F. Fougerousse, Y. Tanizawa, J. Weissenbach, J. S. Beckmann, G. M. Lathrop, Ph. Passa, M. A. Permutt, D. Cohen, Close Linkage of Glucokinase Locus on Chromosome 7p to Early-Onset Non-Insulin-Dependent Diabetes Mellitus Nature. ,vol. 356, pp. 162- 164 ,(1992) , 10.1038/356162A0
E. T. Skarfors, T. A. Wegener, H. Lithell, I. Selinus, Physical training as treatment for Type 2 (non-insulin-dependent) diabetes in elderly men. A feasibility study over 2 years Diabetologia. ,vol. 30, pp. 930- 933 ,(1987) , 10.1007/BF00295876
J.O. Clausen, T. Hansen, C. Bjørbaek, S.M. Echwald, S.A. Urhammer, S. Rasmussen, C.B. Andersen, L. Hansen, K. Almind, O. Pedersen, J.O. Clausen, K. Borch-Johnsen, K. Winther, J. Haraldsdòttir, Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1 The Lancet. ,vol. 346, pp. 397- 402 ,(1995) , 10.1016/S0140-6736(95)92779-4
D. J. Pettitt, W. C. Knowler, P. H. Bennett, K. A. Aleck, H. R. Baird, Obesity in Offspring of Diabetic Pima Indian Women Despite Normal Birth Weight Diabetes Care. ,vol. 10, pp. 76- 80 ,(1987) , 10.2337/DIACARE.10.1.76
H. Kuroyama, T. Sanke, S. Ohagi, M. Furuta, H. Furuta, K. Nanjo, Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects Diabetologia. ,vol. 37, pp. 536- 539 ,(1994) , 10.1007/S001250050144
SIMEON I. TAYLOR, ALESSANDRO CAMA, DOMENICO ACCILI, FABRIZIO BARBETTI, EIICHI IMANO, HIROKO KADOWAKI, TAKASHI KADOWAKI, Genetic basis of endocrine disease. 1. Molecular genetics of insulin resistant diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. ,vol. 73, pp. 1158- 1163 ,(1991) , 10.1210/JCEM-73-6-1158