Clinical Reality and Treatment for Local Recurrence of Rectal Cancer: A Single-Center Retrospective Study.

摘要: Background and Objectives: Despite advances in treatment, local recurrence remains a great concern patients with rectal cancer. The aim of this study was to investigate the incidence risk factors cancer our single center over 7-year-period. Materials Methods: Patients stage I-III were treated curative intent. necessity for radiotherapy chemotherapy determined before surgery and/or postoperative histopathological results. Results: Of 365 patients, 76 (20.8%) developed recurrent disease. In total, 27 (7.4%) presented tumor (isolated 40.7% cases). Radiotherapy performed 296 (81.1%) patients. most often used schema 5 × Gy followed by immediate (n = 214, 58.6%). Local occurred less frequently 9, 4%). Surgical procedures relapses 12 six whom operated radical Only two lived more than years after treatment. associated primary distal location worse prognosis. median overall survival treatment 19 months. Conclusions: Individualized patient selection systematic algorithms should be clinical practice minimize likelihood relapse. allows good control resectable cT2N+/cT3N0 Radical resection isolated offers best chances cure.