E2F-2, a novel mammalian transcription factor
作者： David C. Heimbrook , Allen I. Oliff , Mona Ivey-Hoyle
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摘要: The present invention is directed to a novel protein with E2F-like properties and the cDNA that encodes for protein. purified exhibits biological activity which deemed important medical science in study of cell cycle regulation general specific Rb rumor suppressor certain viral oncogenes. may be employed complex pRb or other cellular proteins inhibitors biochemical transformations those proteins, such as example phosphorylation portion complex, therefore aiding potential pharmaceutical agents useful against oncoproteins encoded by DNA tumor viruses.
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