Ovarian mixed germ cell tumor with yolk sac and teratomatous components in a dog.

摘要: Mixed germ cell tumors of the ovary have rarely been reported in veterinary species. A 3-year-old intact female Labrador Retriever dog was presented for lethargy, abdominal distention, and a midabdominal mass. An exploratory laparotomy revealed large (23 cm diameter) left ovarian tumor multiple small (2-3 pale tan masses on peritoneum surface diaphragm. Histological examination mixed with yolk sac component rare Schiller-Duval bodies teratomatous comprised primarily neural differentiation. The metastases were solely component. diffusely immunopositive cytokeratin scattered cells reactive α-fetoprotein placental alkaline phosphatase. Within component, neuropil S100, neuron-specific enolase, neurofilaments few glial fibrillary acidic protein cells. Ovarian may be pure consist only 1 element or include more than element, such as teratoma tumor.