Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance

作者: Fung Zhao , Michelle KY Siu , LiLi Jiang , Kar Fai Tam , Hextan YS Ngan

DOI: 10.1371/JOURNAL.PONE.0113478

关键词:

摘要: Aim Deregulation of FOXM1 has been documented in various cancers. The aim of this study was to evaluate the role of FOXM1 in ovarian cancer tumorigenesis and paclitaxel resistance…

参考文章(29)
David J. Sharp, Gregory C. Rogers, Jonathan M. Scholey, Microtubule motors in mitosis Nature. ,vol. 407, pp. 41- 47 ,(2000) , 10.1038/35024000
Stephen S. Myatt, Eric W. -F. Lam, The emerging roles of forkhead box (Fox) proteins in cancer Nature Reviews Cancer. ,vol. 7, pp. 847- 859 ,(2007) , 10.1038/NRC2223
Chuay-Yeng Koo, Kyle W. Muir, Eric W.-F. Lam, FOXM1: From cancer initiation to progression and treatment Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. ,vol. 1819, pp. 28- 37 ,(2012) , 10.1016/J.BBAGRM.2011.09.004
Michelle K.Y. Siu, Esther S.Y. Wong, Hoi Yan Chan, Daniel S.H. Kong, Nina W.S. Woo, Kar Fai Tam, Hextan Y.S. Ngan, Queeny K.Y. Chan, Dominic C.W. Chan, Kelvin Y.K. Chan, Annie N.Y. Cheung, Differential expression and phosphorylation of Pak1 and Pak2 in ovarian cancer: effects on prognosis and cell invasion. International Journal of Cancer. ,vol. 127, pp. 21- 31 ,(2010) , 10.1002/IJC.25005
David W. Chan, Winnie W. Y. Hui, Patty C. H. Cai, Michelle X. Liu, Mingo M. H. Yung, Celia S. L. Mak, Thomas H. Y. Leung, Karen K. L. Chan, Hextan Y. S. Ngan, Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells PLoS ONE. ,vol. 7, pp. e52578- ,(2012) , 10.1371/JOURNAL.PONE.0052578
Judith K. Wolf, Gordon B. Mills, Lisa Bazzet, Robert C. Bast, Jack A. Roth, David M. Gershenson, Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status Gynecologic Oncology. ,vol. 75, pp. 261- 266 ,(1999) , 10.1006/GYNO.1999.5565
Arata Shimo, Chizu Tanikawa, Toshihiko Nishidate, Meng-Lay Lin, Koichi Matsuda, Jae-Hyun Park, Tomomi Ueki, Tomohiko Ohta, Koichi Hirata, Mamoru Fukuda, Yusuke Nakamura, Toyomasa Katagiri, Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis Cancer Science. ,vol. 0, pp. 071113200227002- ??? ,(2007) , 10.1111/J.1349-7006.2007.00635.X
Christian Pilarsky, Michael Wenzig, Thomas Specht, Hans Detlev Saeger, Robert Grützmann, Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia. ,vol. 6, pp. 744- 750 ,(2004) , 10.1593/NEO.04277
Y Nakamura, F Tanaka, N Haraguchi, K Mimori, T Matsumoto, H Inoue, K Yanaga, M Mori, Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer. British Journal of Cancer. ,vol. 97, pp. 543- 549 ,(2007) , 10.1038/SJ.BJC.6603905
Yoshiya Furusawa, Ken Ohnishi, Tadaaki Kirita, Takeo Ohnishi, Nobuhiro Yamakawa, Akihisa Takahashi, Eiichiro Mori, Yuichiro Imai, High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation Cancer Science. ,vol. 99, pp. 1455- 1460 ,(2008) , 10.1111/J.1349-7006.2008.00818.X